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Taken From a transcript of a Seminar by Dr John R. Lee, M.D.

Progesterone's Role In Making New Bone

     There are little cells that migrate through the bone and they are sniffing out areas where there is old bone. Bone that was made 10 years ago. And they find those areas and they dissolve them away. And those are called the osteoclast cells. Kind of like pacman in the arcades, pacman comes in and eats up the old bone. .... And they leave a little space called a lacuna, a little lake - a little emptiness . Along come the osteoblast. They are related to the osteoclast but they are different. And they come in and they put in nice thick new bone. The new bone can be stronger than the old bone that was removed. Isn't that amazing. The osteoblast only do it at the places where the osteoclast have eaten out old bone. So the bone is always being made, unmade and then made again. The timing of making a hard bone like the femur, the leg bone is about 14-15 years for complete turnover. 100% of it is brand new, all the minerals all the vitamins all the parts of it the collagen the whole part - brand new. Continuously made. Which means every year only 1/15 is being worked on. So it is a slow turnover time. Whereas the bones in your back and in your heal have a turnover time of about 5 years, totally bran new in 5 years. But part was 4 years ago, part 3 years ago and so on. So new bone is made, and then it rests until the time for remaking comes around again 5 or 6 or 15 years later. And this is the whole way bones are made. Progesterone's role is to stimulate these osteoblasts to make new bone. That is the role of progesterone. What estrogen does is to help slow up packman, the osteoclast. It doesn't do anything to make new bone. And you don't have to take my word for it, this is standard - it is being taught now.

Osteoporosis - more info     Much More on Progesterone

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